{{Rsnum
|rsid=910080
|Gene=PDYN
|Chromosome=20
|position=1979580
|Orientation=plus
|GMAF=0.4669
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=PDYN,RP4-684O24.5
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 54.5 | 38.2 | 7.3
| HCB | 2.9 | 21.2 | 75.9
| JPT | 5.4 | 40.2 | 54.5
| YRI | 24.5 | 55.1 | 20.4
| ASW | 21.1 | 57.9 | 21.1
| CHB | 2.9 | 21.2 | 75.9
| CHD | 0.9 | 21.3 | 77.8
| GIH | 20.0 | 53.0 | 27.0
| LWK | 24.5 | 52.7 | 22.7
| MEX | 42.9 | 48.2 | 8.9
| MKK | 23.0 | 55.9 | 21.1
| TSI | 54.0 | 38.0 | 8.0
| HapMapRevision=28
}}{{PMID|18923396|OA=1
}}  In Caucasians, we found point-wise significant associations of 3' UTR SNPs ([[rs910080]], [[rs910079]], and [[rs2235749]]) with [[cocaine]] dependence and cocaine/[[alcohol]] codependence.

{{ neighbor
| rsid = 910079
| distance = 28
}}

{{PMID Auto
|PMID=19468819
|Title=Gene polymorphisms in prodynorphin (PDYN) are associated with episodic memory in the elderly
}}

{{PMID Auto
|PMID=21382455
|Title=Association between heroin dependence and prodynorphin gene polymorphisms
}}

{{PMID Auto
|PMID=22443215
|Title=Genetic association analyses of PDYN polymorphisms with heroin and cocaine addiction.
}}

{{PMID Auto
|PMID=23101464
|Title=Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Illumina Human 1M}}