{{Rsnum
|rsid=9295536
|Gene=LINC00340
|Chromosome=6
|position=22131700
|Orientation=plus
|GMAF=0.3627
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=CASC15
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 14.2 | 51.3 | 34.5
| HCB | 54.0 | 35.0 | 10.9
| JPT | 46.9 | 49.6 | 3.5
| YRI | 78.2 | 21.1 | 0.7
| ASW | 73.7 | 26.3 | 0.0
| CHB | 54.0 | 35.0 | 10.9
| CHD | 62.4 | 29.4 | 8.3
| GIH | 28.7 | 52.5 | 18.8
| LWK | 70.9 | 27.3 | 1.8
| MEX | 48.3 | 41.4 | 10.3
| MKK | 63.2 | 33.5 | 3.2
| TSI | 17.6 | 52.0 | 30.4
| HapMapRevision=28
}}
SNPs clustered in one region of chromosome 6p22 have been linked to increased risk for the exceedingly rare childhood cancer known as [[neuroblastoma]]. A study involving 720 patients determined that [[rs9295536]](A;A) genotypes had increased likelihood of [[neuroblastoma]] development (odds ratio 1.93, CI: 1.55 to 2.40, p=8 x 10<sup>-8</sup>). At-risk homozygotes diagnosed with [[neuroblastoma]] had, on average, more malignant clinical presentation, more aggressive disease, and poorer long-term survival.{{PMID|18463370|OA=1
}} 

For more information on this cluster of SNPs, see [[rs6939340]].

{{omim
|id=256700
|desc=NEUROBLASTOMA
|rsnum=9295536
}}

{{omim
|id=613015
|rsnum=9295536
}}

{{PMID Auto
|PMID=19412175
|Title=Common variations in BARD1 influence susceptibility to high-risk neuroblastoma.
|OA=1
}}

{{PMID Auto GWAS
  |PMID=22941191
  |Trait=Neuroblastoma
  |Title=Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma.
  |RiskAllele=A
  |Pval=8E-16
  |OR=1.36
  |ORtxt=[NR]
  |OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}