{{Rsnum
|rsid=932275
|Gene=HTRA1
|Chromosome=10
|position=124231464
|Orientation=plus
|GMAF=0.2994
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.9 | 38.1 | 61.1
| HCB | 18.7 | 51.5 | 29.9
| JPT | 19.6 | 45.5 | 34.8
| YRI | 8.8 | 38.1 | 53.1
| ASW | 0.0 | 45.6 | 54.4
| CHB | 18.7 | 51.5 | 29.9
| CHD | 19.4 | 53.7 | 26.9
| GIH | 13.9 | 46.5 | 39.6
| LWK | 14.7 | 48.6 | 36.7
| MEX | 5.2 | 44.8 | 50.0
| MKK | 12.8 | 44.9 | 42.3
| TSI | 0.0 | 29.4 | 70.6
| HapMapRevision=28
}}[http://www.nature.com/ng/journal/v40/n7/full/ng.170.html nature] [[age related macular degeneration]] is associated with five highly correlated SNPs ([[rs10490924]], [[rs3750848]], [[rs3793917]], [[rs11200638]] and [[rs932275]]; r2 < 0.88) showed strongest association with AMD (2.72 < OR < 2.86)

{{PMID Auto
|PMID=19933195
|Title=Analysis of six genetic risk factors highly associated with AMD in the region surrounding ARMS2 and HTRA1 on chromosome 10q26
}}

{{PMID Auto
|PMID=17884985
|Title=A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration.
|OA=1
}}

{{PMID Auto
|PMID=21878851
|Title=Association between high-risk disease loci and response to anti-vascular endothelial growth factor treatment for wet age-related macular degeneration.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}