{{Rsnum
|rsid=9376092
|Chromosome=6
|position=135106006
|Orientation=plus
|GMAF=0.2548
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 5.3 | 36.3 | 58.4
| HCB | 10.9 | 38.0 | 51.1
| JPT | 15.0 | 44.2 | 40.7
| YRI | 2.7 | 29.9 | 67.3
| ASW | 1.8 | 36.8 | 61.4
| CHB | 10.9 | 38.0 | 51.1
| CHD | 11.9 | 43.1 | 45.0
| GIH | 3.0 | 23.8 | 73.3
| LWK | 1.8 | 23.6 | 74.5
| MEX | 12.1 | 32.8 | 55.2
| MKK | 6.5 | 36.1 | 57.4
| TSI | 4.9 | 42.2 | 52.9
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19924444
|Trait=Beta thalassemia/hemoglobin E disease
|Title=A genome-wide association identified the common genetic variants influence disease severity in beta(0)-thalassemia/hemoglobin E
|RiskAllele=
|Pval=2E-11
|OR=2.91
|ORtxt=[2.12-3.99]
}}

{{PMID Auto GWAS
|PMID=20183929
|Trait=Beta thalassemia/hemoglobin E disease
|Title=A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.
|RiskAllele=
|Pval=2E-11
|OR=2.9100
|ORtxt=[2.12-3.99]
}}

{{PMID Auto
|PMID=17592125
|Title=Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults.
|OA=1
}}

{{PMID Auto
|PMID=19148297
|Title=Genetic variation on chromosome 6 influences F cell levels in healthy individuals of African descent and HbF levels in sickle cell patients.
|OA=1
}}

{{PMID Auto
|PMID=20401335
|Title=Sickle Cell Disease in the Post Genomic Era: A Monogenic Disease with a Polygenic Phenotype.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs9376092
|overall_frequency_n=37
|overall_frequency_d=128
|overall_frequency=0.289062
|n_genomes=26
|n_genomes_annotated=0
|n_haplomes=30
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}