{{Rsnum
|rsid=9424490
|Gene=LOC645395
|Chromosome=1
|position=232886124
|Orientation=plus
|GMAF=0.1635
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=LOC101927711
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 88.4 | 11.6 | 0.0
| HCB | 75.9 | 23.4 | 0.7
| JPT | 87.5 | 11.6 | 0.9
| YRI | 24.7 | 50.7 | 24.7
| ASW | 47.4 | 38.6 | 14.0
| CHB | 75.9 | 23.4 | 0.7
| CHD | 76.1 | 22.0 | 1.8
| GIH | 88.1 | 11.9 | 0.0
| LWK | 25.5 | 48.2 | 26.4
| MEX | 76.8 | 19.6 | 3.6
| MKK | 37.9 | 47.7 | 14.4
| TSI | 94.1 | 5.9 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs9424490
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19268276
|Annotation=In a GWAS of 3497 Dutch subjects from the Netherlands Study of Depression and Anxiety or from the Netherlands Twin Registry, this SNP was found to be associated with Current Smoking (p = 0.00003618;OR for minor allele G:1.715).
|Drugs=nicotine
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164924496
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs9424490
|overall_frequency_n=26
|overall_frequency_d=128
|overall_frequency=0.203125
|n_genomes=20
|n_genomes_annotated=0
|n_haplomes=24
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}