{{Rsnum
|rsid=9530
|Gene=GUSB
|Chromosome=7
|position=65960907
|Orientation=minus
|ReferenceAllele=C
|MissenseAllele=T
|GMAF=0.4183
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=GUSB
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 28.3 | 49.6 | 22.1
| HCB | 67.9 | 30.7 | 1.5
| JPT | 83.2 | 14.2 | 2.7
| YRI | 8.8 | 38.1 | 53.1
| ASW | 14.0 | 47.4 | 38.6
| CHB | 67.9 | 30.7 | 1.5
| CHD | 74.3 | 22.0 | 3.7
| GIH | 43.6 | 43.6 | 12.9
| LWK | 2.7 | 35.5 | 61.8
| MEX | 32.8 | 48.3 | 19.0
| MKK | 9.6 | 45.5 | 44.9
| TSI | 30.4 | 51.0 | 18.6
| HapMapRevision=28
}}

{{Venter SNP
|rsid=9530
|allele=G
|frequency=0.467
|uid=1103652596568
|type=heterozygous_SNP
|hugo=GUSB
|ensembl gene=ENSG00000169919
|ensembl transcript=ENST00000304895
|sift=TOLERATED
|disease=Defects in GUSB are the cause of mucopolysaccharidosis type VII (MPS-VII) (MIM:253220); also known as Sly syndrome. This is an autosomal recessive disorder characterized by excessive dermatan and heparan sulfates in the urine and Hurler-like features.
}}

{{GET Evidence
|gene=GUSB
|aa_change=Leu649Pro
|aa_change_short=L649P
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs9530
|overall_frequency_n=5215
|overall_frequency_d=10758
|overall_frequency=0.484756
|n_genomes=45
|n_genomes_annotated=0
|n_haplomes=64
|n_articles=0
|n_articles_annotated=0
|qualityscore_in_silico=3
|qualitycomment_in_silico=Y
|gene_in_genetests=Y
|genetests_testable=Y
|nblosum100=7
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}