{{Rsnum
|rsid=966221
|Gene=PDE4D
|Chromosome=5
|position=60206693
|Orientation=minus
|GMAF=0.4922
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=PDE4D
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 28.6 | 57.1 | 14.3
| HCB | 4.4 | 34.1 | 61.5
| JPT | 1.8 | 21.4 | 76.8
| YRI | 30.3 | 51.0 | 18.6
| ASW | 30.4 | 51.8 | 17.9
| CHB | 4.4 | 34.1 | 61.5
| CHD | 5.7 | 29.2 | 65.1
| GIH | 26.7 | 41.6 | 31.7
| LWK | 29.9 | 43.9 | 26.2
| MEX | 43.9 | 42.1 | 14.0
| MKK | 27.3 | 44.2 | 28.6
| TSI | 35.6 | 52.5 | 11.9
| HapMapRevision=28
}}
{{PMID|18694398}} A study of 639 Chinese [[stroke]] patients concluded that the [[rs966221]](C) allele is associated with increased risk for atherothrombotic strokes (odds ratio 1.51, CI: 1.09-2.10) in this population.

{{PMID Auto
|PMID=21677445
|Title=Meta-Analysis of Homogeneous Subgroups Reveals Association between PDE4D Gene Variants and Ischemic Stroke
}}

{{PMID Auto
|PMID=16130105
|Title=Phosphodiesterase 4D and 5-lipoxygenase activating protein in ischemic stroke.
|OA=1
}}

{{PMID Auto
|PMID=16166573
|Title=Association of phosphodiesterase 4D gene with ischemic stroke in a Pakistani population.
}}

{{PMID Auto
|PMID=16835261
|Title=Phosphodiesterase 4D polymorphisms and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women Study.
|OA=1
}}

{{PMID Auto
|PMID=19409523
|Title=Multilocus Bayesian meta-analysis of gene-disease associations.
|OA=1
}}

{{PMID Auto
|PMID=20031584
|Title=Genetics of atherothrombotic and lacunar stroke.
|OA=1
}}

{{PMID Auto
|PMID=20540798
|Title=Sex-differential genetic effect of phosphodiesterase 4D (PDE4D) on carotid atherosclerosis.
|OA=1
}}

{{PMID Auto
|PMID=23786009
|Title=[Association of rs966221 phosphodiesterase 4D gene's polymorphism with risk of myocardial infarction]
}}

{{PMID Auto
|PMID=23774910
|Title=[Association study between PDE4D gene polymorphism and ischemic stroke].
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}