{{Rsnum
|rsid=968567
|Gene=FADS2
|Chromosome=11
|position=61828092
|Orientation=plus
|GMAF=0.07943
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=FADS2
}}One of 42 more SNPs associated with [[rheumatoid arthritis]] based on a meta-analysis of 30,000 patients, most with odds ratios of 1.01 - 1.2. {{doi|10.1038/nature12873}}

{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 4.4 | 28.3 | 67.3
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 8.8 | 91.2
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 8.9 | 91.1
| LWK | 0.0 | 1.8 | 98.2
| MEX | 1.7 | 19.0 | 79.3
| MKK | 0.0 | 3.8 | 96.2
| TSI | 1.0 | 20.6 | 78.4
| HapMapRevision=28
}}
{{PMID Auto
|PMID=19546342
|Title=A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1
|OA=1
}}

{{PMID Auto
|PMID=20427696
|Title=Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios.
|OA=1
}}

{{PMID Auto
|PMID=20565855
|Title=Genetic variation in lipid desaturases and its impact on the development of human disease.
|OA=1
}}

{{PMID Auto
|PMID=21383846
|Title=Genetic variants of the FADS gene cluster and ELOVL gene family, colostrums LC-PUFA levels, breastfeeding, and child cognition.
|OA=1
}}

{{PMID Auto
|PMID=22877655
|Title=Umbilical cord PUFA are determined by maternal and child fatty acid desaturase (FADS) genetic variants in the Avon Longitudinal Study of Parents and Children (ALSPAC)
|OA=1
}}

{{PMID Auto
|PMID=23285256
|Title=Prostatic alpha-linolenic acid (ALA) is positively associated with aggressive prostate cancer: a relationship which may depend on genetic variation in ALA metabolism
|OA=1
}}

{{PMID Auto GWAS
  |PMID=24390342
  |Trait=Rheumatoid arthritis
  |Title=Genetics of rheumatoid arthritis contributes to biology and drug discovery.
  |RiskAllele=C
  |Pval=2E-8
  |OR=1.12
  |ORtxt=[1.07-1.16]
  }}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}