{{Rsnum
|rsid=981782
|Gene=HCN1
|Chromosome=5
|position=45285616
|Orientation=minus
|GMAF=0.3278
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=HCN1
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 16.9 | 44.6 | 38.5
| HCB | 8.9 | 48.9 | 42.2
| JPT | 15.6 | 55.6 | 28.9
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 8.9 | 48.9 | 42.2
| CHD | 43.5 | 54.6 | 1.9
| GIH | 42.9 | 50.0 | 7.1
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 66.7 | 30.3 | 3.0
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=17529967
|Trait=Breast cancer
|Title=Genome-wide association study identifies novel breast cancer susceptibility loci
|RiskAllele=C
|Pval=0.0000090000000000000002
|OR=1.04
|ORtxt=[1.01-1.08]
|OA=1
}}

{{PMID|18326623|OA=1
}} Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.

{{PMID|18681954|OA=1
}} Breast cancer susceptibility loci and mammographic density.

{{PMID|18708391|OA=1
}} Breast cancer risk polymorphisms and interaction with ionizing radiation among U.S. radiologic technologists.

{{PMID|19232126|OA=1
}} Association between breast cancer susceptibility loci and mammographic density: the Multiethnic Cohort.

{{PMID|19304784|OA=1
}} Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study.

{{PMID|19639606|OA=1
}} Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases.

{{PMID|20605201|OA=1
}} Gene-environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women Study.

{{PMID|22045194|OA=1
}} Combined effect of low-penetrant SNPs on breast cancer risk.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs981782
|overall_frequency_n=30
|overall_frequency_d=128
|overall_frequency=0.234375
|n_genomes=22
|n_genomes_annotated=0
|n_haplomes=27
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}