{{Rsnum
|rsid=9818870
|Gene=MRAS
|Chromosome=3
|position=138403280
|Orientation=plus
|GMAF=0.09137
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=MRAS
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 68.1 | 30.1 | 1.8
| HCB | 99.3 | 0.7 | 0.0
| JPT | 83.0 | 17.0 | 0.0
| YRI | 89.0 | 11.0 | 0.0
| ASW | 86.0 | 14.0 | 0.0
| CHB | 99.3 | 0.7 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 85.0 | 15.0 | 0.0
| LWK | 82.6 | 17.4 | 0.0
| MEX | 83.6 | 16.4 | 0.0
| MKK | 88.5 | 11.5 | 0.0
| TSI | 70.6 | 29.4 | 0.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19198612
|Trait=Coronary artery disease
|Title=New susceptibility locus for coronary artery disease on chromosome 3q22.3
|RiskAllele=T
|Pval=7E-13
|OR=1.15
|ORtxt=[1.11-1.19]
|OA=1
}}

{{PharmGKB
|RSID=rs9818870
|Name_s=
|Gene_s=MRAS
|Feature=
|Evidence=PubMed ID:19198612; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: New susceptibility locus for coronary artery disease on chromosome 3q22.3. (Initial Sample Size: 6,990 cases, 8,955 controls; Replication Sample Size: 12,417 cases, 12,411 controls); (Region: 3q22.3; Reported Gene(s): MRAS; Risk Allele: rs9818870-T); (p-value= 0.0000000000007).This variant is associated with Coronary artery disease.
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739956
}}

{{PMID Auto
|PMID=21733517
|Title=Fine mapping of chromosome 3q22.3 identifies two haplotype blocks in ESYT3 associated with coronary artery disease in female Han Chinese
}}

{{PMID Auto
|PMID=19956433
|Title=Genetics of coronary artery disease: focus on genome-wide association studies.
|OA=1
}}

{{PMID Auto
|PMID=20835900
|Title=Genetics of diabetes complications.
|OA=1
}}

{{PMID Auto
|PMID=21984477
|Title=Genomic risk variants at 1p13.3, 1q41, and 3q22.3 are associated with subsequent cardiovascular outcomes in healthy controls and in established coronary artery disease.
}}

{{PMID Auto
|PMID=22664914
|Title=MicroRNA-mediated regulation of gene expression is affected by disease-associated SNPs within the 3'-UTR via altered RNA structure.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs9818870
|overall_frequency_n=13
|overall_frequency_d=128
|overall_frequency=0.101562
|n_genomes=11
|n_genomes_annotated=0
|n_haplomes=11
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto GWAS
  |PMID=24262325
  |Trait=Coronary artery disease
  |Title=Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
  |RiskAllele=T
  |Pval=1E-7
  |OR=1.11
  |ORtxt=[1.07-1.15]
  }}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}