{{Rsnum
|rsid=9886784
|Chromosome=9
|position=1521204
|Orientation=plus
|GMAF=0.2296
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 3.5 | 35.4 | 61.1
| HCB | 3.6 | 35.8 | 60.6
| JPT | 0.9 | 35.4 | 63.7
| YRI | 17.0 | 55.1 | 27.9
| ASW | 14.0 | 36.8 | 49.1
| CHB | 3.6 | 35.8 | 60.6
| CHD | 0.9 | 28.4 | 70.6
| GIH | 7.9 | 44.6 | 47.5
| LWK | 24.8 | 40.4 | 34.9
| MEX | 3.4 | 20.7 | 75.9
| MKK | 11.0 | 54.8 | 34.2
| TSI | 2.9 | 32.4 | 64.7
| HapMapRevision=28
}}[[rs9886784]], a intergenic SNP on chromosome 9, is reported to influence the risk for [[Alzheimer's disease]] based on a study of ~1100 Canadian patients. The risk allele is (A); the odds ratio is 3.23 (CI: 1.79 - 5.84). {{PMID|17998437}}

{{PMID Auto
|PMID=19204163
|Title=GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results.
|OA=1
}}
Meta-analysis did NOT show rs9886784 with consistent evidence for association with AD across the investigated data sets:

Genetic association analysis testing of 4 GWA signals (rs7101429 [GAB2], rs7019241 [GOLM1], rs10519262 [chromosome 15q], and rs9886784 [chromosome 9p]) using family-based methods. In the combined analyses, only rs7101429 in GAB2 yielded significant evidence of association with the same allele as in the original GWA study (P =.002). The results are in agreement with recent meta-analyses of this and other GAB2 polymorphisms suggesting approximately a 30% decrease in risk for AD among carriers of the minor alleles. None of the other 3 tested loci showed consistent evidence for association with AD across the investigated data sets.

{{PMID|19640594|OA=1
}} Recent insights into the molecular genetics of dementia.

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}