{{Rsnum
|rsid=9960767
|Gene=TCF4
|Chromosome=18
|position=55487771
|Orientation=plus
|GMAF=0.08586
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=TCF4
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 86.7 | 12.4 | 0.9
| HCB | 99.3 | 0.7 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 55.1 | 36.7 | 8.2
| ASW | 64.3 | 33.9 | 1.8
| CHB | 99.3 | 0.7 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 54.0 | 41.0 | 5.0
| LWK | 50.5 | 39.3 | 10.3
| MEX | 91.4 | 8.6 | 0.0
| MKK | 37.9 | 47.1 | 15.0
| TSI | 91.2 | 6.9 | 2.0
| HapMapRevision=28
}}
[http://blog.23andme.com/2009/07/03/snpwatch-researchers-show-importance-of-common-dna-variants-in-schizophrenia/ 23andMe blog] [[schizophrenia]]
*[[rs3131296]](C) increased the odds of schizophrenia by 1.19x
*[[rs12807809]](T) increased the odds of schizophrenia by 1.15x
*[[rs9960767]](C) increased the odds of schizophrenia by 1.23 times.

{{PMID Auto GWAS
|PMID=19571808
|Trait=Schizophrenia
|Title=Common variants conferring risk of schizophrenia
|RiskAllele=C
|Pval=4E-9
|OR=1.23
|ORtxt=[NR]
|OA=1
}}

{{omim
|id=181500
|rsnum=9960767
}}

{{PMID Auto
|PMID=21543597
|Title=The Schizophrenia Risk Allele C of the TCF4 rs9960767 Polymorphism Disrupts Sensorimotor Gating in Schizophrenia Spectrum and Healthy Volunteers
}}

{{PMID Auto
|PMID=21812098
|Title=Association between TCF4 and schizophrenia does not exert its effect by common nonsynonymous variation or by influencing cis-acting regulation of mRNA expression in adult human brain
|OA=1
}}

{{PMID Auto
|PMID=22451930
|Title=Schizophrenia risk polymorphisms in the TCF4 gene interact with smoking in the modulation of auditory sensory gating
|OA=1
}}

{{PMID Auto
|PMID=20485477
|Title=New Genetic Findings in Schizophrenia: Is there Still Room for the Dopamine Hypothesis of Schizophrenia?
|OA=1
}}

{{PMID Auto
|PMID=21228604
|Title=Novel schizophrenia risk gene TCF4 influences verbal learning and memory functioning in schizophrenia patients.
}}

{{PMID Auto
|PMID=21932083
|Title=Impact of TCF4 on the genetics of schizophrenia.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs9960767
|overall_frequency_n=19
|overall_frequency_d=126
|overall_frequency=0.150794
|n_genomes=14
|n_genomes_annotated=0
|n_haplomes=17
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=22005930
|Title=Genome-wide association study of Alzheimer's disease with psychotic symptoms.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}